Live from New York, it's... Andy Samberg!
Sketches include "A Message from Kevin Federline," "Veritas Ultrasound HD," "2007 National Douchebag Championships," "MacGruber" (three parts), "Jeremy and Sasha," "Fred Thompson '08," "America's First Colonists," "Rowlf & The Swedish Chef," and "Mad Joe Dixon."
Spoon performed "The Underdog" and "You Got Yr. Cherry Bomb."
Live from New York, it's... Amy Poehler!
Sketches include "The All-But-Certain-To-Be-Next-President," "Angry Dog," "Penelope's Charity Auction," "High School Musical 3," "Iran So Far" (digital short), "Read to Achieve," "The Lyle Kane Show," "The Best of Solid Gold," "Ambiguously Gay Duo" (cartoon), "106 & Park," and "Great Moments in Guidance Counseling."
Kanye West performed "Stronger", "Good Life", "Champion", and an improvised version of "Everything I Am."